Refractory Acute Graft vs Host Disease

Day + 44

Sam again.

Graham's nausea and vomitting has stopped but he has developed very bad diarrhea which is worsened today. He is now considered to have Refractory Acute Graft Vs Host Disease of the Gut, ie; it is not responding to the steriods.

This is a very bad position to be in so they are starting him on a clinical trial as there is no standard form of treatment for this condition.

Although he now has no leukaemia present, this is a very serious situation and if he is going to respond, we should see some improvement in the next 36 hours.

Please keep him in your thoughts and I will update tomorrow.